Volume 2 Issue 1
UBIAD1, a Prenyltransferase Enzyme Modulates Biological Functions Required for the Intracellular Homeostasis Maintenance
Samira Zohra Midoun, Fengsen Duan, Yan Xia, Junli Liu, Zhiliang Xu, Ling Hong*
Ever since a human version of Drosophila heixuedian (heix) has been identified as a tumor suppressor protein, a pertinent literature got deep interest to the human UBIAD1 protein, in terms to further evaluate the occurred molecular mechanism driving its function in human beings. Ubiad1 is a gene ubiquitously expressed in normal human tissues. The protein harbors a prenyltransferase functional domain conserved throughout the evolution.
Identifying Genetic Risk Factors for Low Ovarian Response
Carolyn Coulam*, Hosam Zaki, Larry Fishel, Hisham Greiss
One of the most frustrating problems in IVF today is that of poor ovarian response. This event has been called poor ovarian reserve, low ovarian reserve, diminished ovarian reserve, premature ovarian aging, and premature ovarian insufficiency. The number of oocytes retrieved directly influences success rates after in vitro fertilization (IVF) and embryo transfer (ET). Poor ovarian response reduces the number of embryos generated and results in decreased pregnancy rates in both index and subsequent IVF cycles.